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Ian I. Joffe, M.D.

CURRICULUM VITAE

Ian I. Joffe, M.D., F.A.C.C.

1105 Laurel Oak Rd., Suite 165
Voorhees, NJ 08043
856/424-3600

PERSONAL DATA

Date of Birth: 1963
Place of Birth: Cape Town, South Africa

EDUCATION

Graduate
1/89-12/89
University of Cape Town Medical School
South Africa
Degree: B. Sc. (Hon)

Undergraduate
2/82-12/87
University of Cape Town Medical School
South Africa
Degree: M.B., Ch.B.
Degree awarded with distinction in the clinical examinations

POSTGRADUATE TRAINING

12/93-11/94
Resident, Internal Medicine
Albert Einstein Medical Center
Philadelphia, PA (PGY3)

12/92-11/93
Resident - Internal Medicine
Albert Einstein Medical Center
Philadelphia, PA (PGY2)

12/91-11/92
Intern in Medicine
Albert Einstein Medical Center
Philadelphia, PA (PGY1)

1/88-12/88
Rotating Internship
Groote Schuur Hospital
Cape Town, South Africa

BOARD CERTIFICATION

Internal Medicine
Cardiovascular Diseases

POSTDOCTORAL TRAINING

7/95-6/98
Clinical Cardiology Fellow, Division of Cardiology
Beth Israel Hospital, Harvard Medical School
Boston, MA

12/94-6/95
Research Fellow, Division of Cardiology
Albert Einstein Medical Center
Philadelphia, PA

1/90-11/91
Research Fellow, Division of Endocrinology
Albert Einstein Medical Center
Philadelphia, PA

CERTIFICATION

Foreign Medical Graduate Certificate
American Board of Internal Medicine, Internal Medicine
American Board of Internal Medicine, Cardiovascular Diseases
American Board of Vascular Medicine

AWARDS AND HONORS

1999 Teaching Award
West Jersey Hospital, Voorhees, NJ

1996 American College of Cardiology/ American Heart Association/Genentech Cardiovascular Meetings Grant Recipient

1995 American College of Cardiology/ American Heart Association/Genentech Cardiovascular Meetings Grant Recipient

1993 Teaching Award
Albert Einstein Medical Center, Philadelphia, PA

1992 American Federation for Clinical Research Trainee Travel Award Baltimore, MD

1989 Medical Research Council of South Africa Research Scholarship

MEMBERSHIPS IN PROFESSIONAL SOCIETIES

American Heart Association
American Medical Association
Camden County Medical Society
American Society of Echocardiology
American Society of Nuclear Cardiology

ACADEMIC APPOINTMENTS

12/99-8/04
Clinical Assistant Professor of Medicine
Hahnemann University School of Medicine
Philadelphia, PA

7/97-6/98
Instructor in Clinical Medicine
Harvard Medical School
Boston, MA

EDUCATIONAL ACTIVITIES

2002-Present
Chairman, Virtua General IRB
Virtua, West Jersey Health System
Voorhees, NJ

1995 Nominated for Teaching Award
Harvard Medical School

1990-1995
Research Fellow and Senior Resident
Albert Einstein Medical Center, Philadelphia, PA
Lectures on clinical methods for medical students

RESEARCH ACTIVITIES

Principal Investigator - STAMINA Trial - Study of anemia in a heart failure population - observational heart failure registry study.

Sub-Investigator - CLARITY Trial - Clopidogrel as adjunctive reperfusion therapy - thrombolysis in MI - TIMI 28

Sub-Investigator - ATTACH Trial - Assessment of Toprol XL taken in combination with hydrochlorothiazide. (2003-2004)

Sub-Investigator - Early ACS (2004)

Principal Investigator - Re-Ly (2006)

Sub-Investigator - IMPROVE-IT (2006)

Sub-Investigator - Durability (start 2007)

BIBLIOGRAPHY

ORIGINAL REPORTS

Stein B, Takizawa M, Katz I, Joffe I, Berlin J, Fallon M, Epstein S: "Salmon Calcitonin Prevents Cyclosporin-A-Induced High Turnover Bone Loss." Endocrinology 129:92-8, 1991

Jacobs TW, Katz IA, Joffe II, Stein B, Takizawa M, Epstein S: "The Effect of FK506, Cyclosporin-A, and Cyclosporin-G on Serum 1,25-dihydroxy vitamin D Levels." Transplantation Procardia. 23:3200-1, 1991

Katz IA, Takizawa M, Joffe II, Stein B, Fallon MD, Epstein S: "Comparison of the Effects of FK506 on Bone Mineral Metabolism in the Rat. A Pilot Study." Transplantation 52(3):571-4, 1991

Joffe I, Katz I, Jacobs, T, Stein B, Takizawa M, Liu C, Berlin J, Epstein S: "17B Estradiol Prevents Osteopenia in the Oophorectomized Rat Treated with Cyclosporin A." Endocrinology 130:1578-86, 1992

Katz IA, Jee WSS, Joffe II, Stein B, Takizawa M, Jacobs TW, Setterberg R, Lin BY, Tank LY, Ke HZ, Zeng QQ, Berlin J, Epstein S: "Prostaglandin E2 Alleviates Cyclosporin A-Induced Bone Loss in the Rat." J. Bone Miner Res. 7(10):1191-200, 1992

Joffe I, Katz I, Sehgal S, Bex F, Kharode Y, Tamasi J, Epstein S: "Lack of Change of Cancellous Bone Volume with Short-Term Use of the New Immunosuppressant Rapamycin in Rats." Calcified Tissue Inter. 53:45-52, 1993

Katz I, Li M, Joffe I, Stein B, Jacobs T, Liang XG, Ke HZ, Jee W, Epstein S: "Influence of Age on Cyclosporin A-Induced Alterations in Bone Mineral Metabolism in the Rat in Vivo." J. Bone Miner Res. 9(1):59-67, 1994

Epstein S, Takizawa M, Stein B, Katz IA, Joffe II, Jacobs TW, Romero D, Liang XG, Li M, Ke HZ, Jee WSS, Berlin J: "The Effect of Cyclosporin A on Bone Mineral Metabolism in Experimental Diabetes Mellitus in the Rat." J. Bone Miner Res. 9:557-66, 1994

Joffe II, Lampert C, Jacobs LE, Owen AN, Ioli A, Kotler MN: "Cardiac Sarcoidosis Masquerading as a Metastatic Tumor: The Role of Transthoracic and Transesophageal Echocardiography." J. Am. Soc. Echocardiogr. 8:933-7, 1996

Joffe II, Jacobs LE, Owen AN, Ioli A, Kotler MN: "Mycotic Aneurysm of the Descending Thoracic Aorta: The Role of Transthoracic and Transesophageal Echocardiography." J. Am. Soc. Echocardiogr. 8:663-7, 1996

Joffe II, Jacobs LE, Kotler MN: "Pericardial Tamponade. Images in Cardiovascular Medicine." J. Am. Soc. Circulation 94:2667, 1996

Joffe II, Jacobs LE, Owen AN, Ioli A, Weiss SE, Nakhjavan FK, Mayer TG, Kotler MN: "Tricuspid papillary Muscle Rupture After Coronary Artery Bypass Surgery: Identification by Transesophageal Echocardiography." Am. Heart J. 132:1055-58, 1996

Joffe II, Douglas PS: "Cardiac Tamponade in Association with an Atrial Septal Defect: Echocardiographic Doppler and Hemodynamic Observations." J. Am. Soc. Echocardiogr. 9:909-14, 1996

Joffe II, Riley MF, Katz SE, Ginsburg GS, Douglas PS: "Acquired Dynamic Left Ventricular Outflow Tract Obstruction Complicating Acute Anterior Myocardial Infarction: Serial Echocardiographic and Clinical Evaluation." J. Am. Soc. Echocardiogr.,10:717-21, 1997

Joffe II, Travers KE, Perreault-Micale C, Hampton T, Katz SE, Morgan JP, Douglas PS: "Abnormal Cardiac Function in the Streptozotocin-Induced, Non-Insulin Dependent Diabetic Rat: Non-Invasive Assessment with Echocardiographic-Doppler and the Contribution of the Nitric Oxide Pathway." Journal American College of Cardiology, 34:2111-9, 1999.

REVIEWS AND EDUCATIONALLY RELEVANT PUBLICATIONS

Joffe I, Epstein S: "Osteoporosis Associated with Rheumatoid Arthritis: Pathogenesis and Management." Seminars Arthritis Rheum. 20:256-72, 1991

Joffe I: "Cigarette Smoking and Facial Wrinkling." Ann. Intern. Med. 115:659, 1991 [Letter]

Joffe I: "The Emergence of Drug-Resistant Tuberculosis in New York City." New Engl. J. Med. 329:134, 1993 [Letter]

Joffe I: "Withdrawal of Digoxin from Patients with Chronic Heart Failure Treated with Angiotensin-Converting-Enzyme Inhibitors." New Engl. J. Med. 329:1820, 1993 [Letter]

Joffe II, Lampert C, Jacobs LE, Kotler MN: "Atherosclerotic Disease of the Aortic Arch and the Risk of Stroke." New Engl. J. Med. 332:1237, 1995 [Letter]

Joffe, II. "Predictors of Systemic Embolism in Mitral Stenosis." Ann Intern Medication, 129:1077-8, 1998

Joffe II, Jacobs LE, Owen AN, Ioli A, Kotler MN: "Non-Infective Valvular Masses." Am. Heart J. 131:1175-83, 1996 [A review of the literature with emphasis on imaging techniques and management.)

Joffe II, Lampert C, Jacobs LE, Owen AN, Kotler MN: "AThe Role of Echocardiography in the Management of Patients Undergoing Open Heart Surgery." Am. Heart J. 131:162-76, 1996 [A review.]

Joffe II, Morgan JP: "Cardiac Evaluation of the Patient Undergoing Non-Cardiac Surgery." Up to Date 1995, 1996, 1997, 1998

Joffe II: "The Risk of Stroke in Atrial Fibrillation." Ann. Internal Medicine 1999

Joffe, II: "The Assessment of Cardiovascular Risk In Patients Undergoing Non-Cardiac Surgery." Up to Date 1997 -Present

ABSTRACTS

Adeleke KT, Owen AN, Ioli AW, Oliner CM, Kotler MN, Joffe II, Lampert C, Jacobs LE: "Can Atropine Requirement be Predicted Early During Dobutamine Stress Echocardiography?" J. Am. Soc. Echocardiogr. 1995 (Abstract)

Joffe II, Travers KE, Perreault-Micale CL, Hampton TG, Katz SE, Morgan JP, Douglas PS: "Impaired Nitric Oxide Availability Contributes to the Cardiac Dysfunction of Diabetes." Circulation 1997

Joffe II, Travers KE, Douglas PS: "Diabetes Contributes to the Adverse Remodeling Post-Infarction." J. Am. Soc. Echocard. 1999

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