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Kenneth Khaw, M.D.

CURRICULUM VITAE

Kenneth Khaw, M.D., A.C.P., F.A.C.C.

1 Brace Road, Suite C
Cherry Hill, NJ 08034
Tel (856) 428-4100
Fax (856) 428-5748

PERSONAL DATA

Date of Birth: 1961

EDUCATION

Graduate
May 1988
New York Medical College
Valhalla, New York
Degree: M.D.

Undergraduate
June 1984
University of Pennsylvania
Philadelphia, Pennsylvania
Degree: B.S. - Bioengineering
Minor in chemical engineering
Training in system design and electronics

POSTGRADUATE TRAINING

7/1/1988-6/30/1991
Resident - Internal Medicine
University of Medicine and Dentistry of New Jersey
Robert Wood Johnson Medical School
New Brunswick, New Jersey

7/1/1991-6/30/1994
Fellow - Cardiovascular Diseases and Hypertension
University of Medicine and Dentistry of New Jersey
Robert Wood Johnson Medical School
New Brunswick, New Jersey

BOARD CERTIFICATION

Internal Medicine
Cardiology

AWARDS AND HONORS

5/2/1994
Trainee Investigator Award presented at the Clinical Research Meeting in Baltimore, Maryland

HOSPITAL AFFILIATIONS

AtlantiCare Regional Medical Center, Pomona, NJ
Our Lady of Lourdes Medical Center, Camden, NJ
Robert Wood Johnson University Hospital, New Brunswick, NJ

ACADEMIC APPOINTMENTS

1995-Present Assistant Professor
University of Medicine and Dentistry of New Jersey
Robert Wood Johnson Medical School
Piscataway, New Jersey

PROFESSIONAL AFFILIATIONS

American College of Cardiology
American College of Physicians
American Heart Association
American Medical Association

CLINICAL RESEARCH

Co-Investigator in Multicenter Trials: TARGET, ESPIRIT, TIMI-4, 14 and 18, JUMBO TIMI-26, GUSTO2-B, SHOCK, REPLACE 1 and 2, In-Time 1 and OAT (Open Artery Hypothesis), AGENT 3 (Angiogenic Gene Therapy, Berlex), BAAMI (Bivalirudin in Acute Myocardial Infarction), VALOR (Visipaque versus Optiray), PD21 Analysis in high risk patient.

INVESTIGATIONAL DEVICES AND STUDIES

Co-investigator in the following trials with Dr. Jai Agarwal:

X-Tract B a thrombectomy device (X-Sizer) to be used in the coronaries and grafts. Percutaneous direct myocardial revascularization for intractable angina.

Principle investigator for 15-lead ECG during angioplasty. Published finding in the American Heart Journal.

Principal investigator for ongoing development of percutaneous ventricular assist device to be used in coronary artery bypass grafting, cardiogenic shock, and congestive heart failure. Animal Study to be submitted for IACUC.

Principal investigator for ongoing development of percutaneous replaceable valves, where valves, in general, can be exchanged percutaneously.

Principal investigator on human study of 3-D coronary angiography with MRI and rotational angiography. IRB Review is pending on resubmission.

Principal investigator for studying near infrared spectrum absorptions in brain tissues for oxygenation and cellular activity. Animal study B IACUC approved.

CATH LAB EXPERIENCE

1. Coronary angiogram and revascularization using radial and brachial arterial approach.
2. AngioJet thrombectomy.
3. TEC - thrombectomy.
4. Rotablation.
5. Intravascular ultrasound of the coronary arteries (Jomed and Boston Scientific ultrasound equipment).
6. Coronary pressure wire measurements.
7. Coronary Doppler flow measurements.
8. Brachytherapy with Novoste System - pending on CheckMate and Guidant system.
9. Peripheral procedures and angiography of iliacs, renals, and others.
10. Rotational angiography from Philip.

PUBLICATIONS

Feng M, Li JK-J, Drzewiecki GM, Khaw K: "Vascular Effects in Concentric Cardiac Hypertrophy: A Model-Based Study." Proc. 2nd International Cardiovasc. Sci. and Med. Conf. p.36, 2003.

Li JK-J, Zhu y, Khaw K, Feng M, Zhang H, Chung J, Kaya M, Atlas G: "Pulse Wave Velocity and Wave Reflections in Assessing Vascular Function." Proc. 2nd International Cardiovasc. Sci. and Med. Conf. p.34, 2003.

Li JK-J, Drzewiecki G, Baron T, Khaw K, Kedem J: "Myocardial Stunning Analyzed by a Single Muscle Fiber Model." Proc. 25th IEEE Eng. Med. Biol. Soc. Conf. p.126(1-3), 2003.

Matonick JP, Li JK-J, Kedem J, Khaw K: "Vasoactive Stimulations on Ventricular and Arterial System Performance." Cardiovasc. Eng. 2:23-32, 2002.

Li JK-J, Matonick JP, Kerkhof PLM, Khaw K: "Response of the Vascular System to Alteration in Ventricular Elastance." Proc. XV International Congress Cardiovasc. System Dynamics Sendai, Japan, p.61, 2002.

Feng M, Li JK-J, Khaw K, Drzewiecki GM: "Progression of Left Ventricular Wall Thickness During Pressure Overload." Proc. 2nd Joint BMES and EMBS Internat. Conf. p.240, 2002.

Matonick JP, Pan RL-C, Hsieh RJ-C, Khaw K, Li JK-J: "Response of the Vascular System to Alteration in Cardiac Contractility." Proc. 2nd Joint BMES and EMBS Internat. Conf. p.241, 2002.

Liao J, Khaw K, Li JK-J: "Fractional Flow Reserve in Coronary Artery Stenosis and Hypertension." Proc. 28th NE Bioeng. Conf. pp.105-106, 2002.

Li JK-J, Matonick JP, Khaw K, Kedem J, Kerkhof PLM: "Augmentation Index: Hemodynamic Basis and Rapid Vascular Afterload Assessment." FASEB J. 15:A1141, 2001.

Matonick JP, Khaw K, Li JK-J: "In Vivo Evaluation of Coronary Stenotic Severity During Routine Cardiac Catheterization from Flow Independent Analysis of Hemodynamic Parameters." FASEB J. 15:A766, 2001.

Li JK-J, Zhu Y, Drzewiecki GM, Khaw K, Agarwal JB: "Nonuniform Geometric and Elastic Properties of Arteries: Local and Global Characterization." Proc. 26th NE Bioeng. Conf. pp.37-38, 2000.

Xiao J, Li JK-J, Drzewiecki GM, Kedem J, Khaw K, Agarwal JB: "Ventricular Relaxation Phase in Myocardial Ischemia: Model-Based Global and Regional Assessments." Proc. 26th NE Bioeng. Conf. pp.129-130, 2000.

Khaw K, Moreyra AE, Tannenbaum AK, Hosler MH, Brewer T, Agarwal JB: "Improvement in Detection of Posterior Ischemia Using 15-Lead Electrocardiogram." Am. Heart J. 138:934-940, 1999.

Agarwal JB, Khaw K, Aurignac F, LoCurto A: "Importance of Posterior Chest Leads in Patients with Suspected Myocardial Infarction, but Nondiagnostic Routine 12-Lead Electrocardiogram." Am. J. Cardiology 83(3):323-326, 1999.

Khaw K, Moreyra AE, Tannenbaum AK, Agarwal JB: "Importance of Posterior Chest Leads: Extra 3 Leads Significantly Increases Detection of Circumflex Ischemia Over Routine 12-Lead Electrocardiogram." Circulation 94(supplement):1-323 (abstract), 1996.

Khaw K, Kotzer W, Eboll D, Wilson A, Moryera AE: "Epicardial Coronary Vasoconstriction Induced by Ramiprilat in Dogs." Clinical Research 42:161A (abstract), 1994.

Khaw K, Kuntz G, Shindler D, Kostis J: "Low Cost Hardware-Software Applications for Quantitative Angiography." JACC 19A:11A (abstract), 1992

Khaw K, Shindler D, Lacy C, Kostis J: "Signal-Averaged Electrocardiography in Elderly Patients with Isolated Systolic Hypertension." RBM 7th International Congress - Cardiostim 90 12:535 (abstract), 1990.

ORAL PRESENTATIONS

Khaw K, Moreyra AE, Tannenbaum AK, Agarwal JB: "Importance of Posterior Chest Leads: Extra 3 Leads Significantly Increases Detection of Circumflex Ischemia Over Routine 12-Lead Electrocardiogram." Circulation 94(supplement):1-323 (abstract), 1996. Presented at the American Heart Association meeting in New Orleans, 1996.

POSTER PRESENTATIONS

Khaw K, Kotzer W, Eboll D, Wilson A, Moryera AE: "Epicardial Coronary Vasoconstriction Induced by Ramiprilat in Dogs." American Federation of Clinical Research Meeting, Baltimore, Maryland, April 1994.

Khaw K, Kuntz G, Shindler D, Kostis J: "Low Cost Hardware-Software Applications for Quantitative Angiography." American College of Cardiology Meeting, Dallas, Texas, March 1992.

Khaw K, Moreyra AE, Tannenbaum AK, Agarwal JB. Poster presentation on anterior ST depression. American College of Cardiology Meeting, Anaheim, California, March 1996.

Li JK-J, Zhu y, Khaw K, Feng M, Zhang H, Chung J, Kaya M, Atlas G: "Pulse Wave Velocity and Wave Reflections in Assessing Vascular Function." Second International Interdisciplinary Conference of Cardiovascular Medicine, Surgery, Science and Mechanics, Bethesda, Maryland, July 23-25, 2003.

Khaw K, Agarwal JB, Koryan A, Ranjan R, Chander A: "Theoretical Analysis of Bifurcating Branch Vessel Geometry for Stents." 27th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interventions, San Diego, California, March 28 - April 1, 2004.

PATENTS WITH UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY, ROBERT WOOD JOHNSON MEDICAL SCHOOL

Percutaneous Ventricular Assist Device: US Patent Pending #20030235086

Open lumen sheaths for guide wire placement; US Patent Pending #20030149444

Needle Guard system; Provisional Patent has been applied.

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