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Richard L. Perlman, M.D., Ph.D.

CURRICULUM VITAE

Richard L. Perlman, M.D., Ph.D.

1105 Laurel Oak Rd., Suite 165
Voorhees, NJ 08043
Tel (856) 424-3600
Fax (856) 424-7154

PERSONAL DATA

Date of Birth: 1951

EDUCATION

Graduate
9/1980-6/1984
New York Medical College
Valhalla, NY
Degree: M.D.

Undergraduate
9/1975-6/1980
New York Medical College
Graduate School of Basic Medical Sciences Valhalla, NY
Degree: Ph.D., Pharmacology
Thesis: "An Investigation of Cardiovascular Changes Produced by the Injection of aconitine at the Area of the Locus Coeruleus in Unanesthetized Rats."

Undergraduate
9/1969-6/1973
University of Rochester
Rochester, NY
Degree: B.A. with Distinction

POSTGRADUATE TRAINING

7/1984-6/1987
Internship, Residency - Internal Medicine
Westchester County Medical Center
Valhalla, NY
Richard Levere, M.D., Program Director

7/1987-6/1988
Fellowship - Cardiology
Hahnemann University Hospital
Philadelphia, PA
Gary Mintz, M.D., Program Director

7/1988-6/1990
Fellowship - Cardiology and Electrophysiology
Hospital of the University of Pennsylvania
Philadelphia, PA
Mark Josephson, M.D., Program Director

BOARD CERTIFICATION

Internal Medicine
Cardiovascular Diseases

HOSPITAL AFFILIATIONS

Virtua-West Jersey Health System, Camden, Voorhees, Marlton, Berlin, NJ
Our Lady of Lourdes Medical Center, Camden, NJ
Underwood Memorial Hospital, Woodbury, NJ
Marlton Rehabilitation Hospital, Marlton, NJ

HONORS AND AWARDS

9/1975-6/1980
Tuition Fellowship and Teaching Assistantship
Department of Pharmacology
New York Medical College, Valhalla, NY

7/1982-8/1982
Summer Student Fellowship in Clinical Pharmacology
New York Medical College, Valhalla, NY

PROFESSIONAL AFFILIATIONS

Associate Member, American College of Physicians
Fellow, American College of Cardiology
American Medical Association
Camden County Medical Society
Medical Society of New Jersey

CLINICAL ACTIVITIES

Primary and consultative cardiology care and interpretation of noninvasive cardiology studies at Our Lady of Lourdes Hospital, Camden, New Jersey, and at the Voorhees, Camden, Marlton and Berlin Divisions of the West Jersey Health System.

Primary and consultative cardiology care and interpretation of noninvasive cardiology studies at Underwood Memorial Hospital, Woodbury, New Jersey, and at Hahnemann University Hospital, Philadelphia, Pennsylvania.

Primary and consultative cardiology care and interpretation of noninvasive cardiology studies for patients of Associated Cardiovascular Consultants, Haddonfield, New Jersey.

Principal investigator for the PURSUIT Trial - A randomized double blind evaluation of the efficacy and safety of two dosing regimens of integrelin versus placebo for reducing mortality and myocardial re-infarction in patients with unstable angina and non Q wave myocardial infarction at the West Jersey Hospital, Voorhees Division, and West Jersey Hospital, Marlton Division, study sites.

Principal Investigator for the ENABLE Trial - a multicenter, double-blind, placebo controlled, randomized study of the effects of Bosentan given twice daily for estimated average followup for 18 months. The primary objective is to evaluate the effects of Bosentan on patients with chronic heart failure.

Principal Investigator for the SAGE Trial - A prospective, randomized, double-blind, multi-center study comparing the effects of aggressive lipid lowering with moderate lipid lowering on the reduction of myocardial ischemia in the elderly as measured by Holter monitoring by comparing two statins.

Principal Investigator for the IMPACT Trial - The impact of medical subspecialty on patient compliance to treatment. Also, it is designed to better define the risk of liver function test abnormalities in a broad group of patients taking Advicor.

Principal Investigator - CLARITY Trial - Clopidogrel as adjunctive reperfusion therapy - thrombolysis in myocardial infarction - TIMI 28

Principal Investigator - ATTACH Trial - Assessment of Toprol XL taken in combination with hydrochlorothiazide. (2003-2004)

Sub-Investigator -OASIS 5 Trial - Evaluating the efficacy and safety of Fondaparinux vs. enoxaparin in acute treatment of unstable angina or non-ST segment elevation MI ACS.

Principal Investigator - Early ACS (2004)

Principal Investigator - CAPABLE (2004)

Principal Investigator - Coreg (2005-2006)

Sub Investigator - Re-Ly (2006)

Sub-Investigator - Improve-It (2006)

BIBLIOGRAPHY

PUBLICATIONS

Perlman R, Lehr D, Guideri G: "Hypertension and Pulmonary Edema After Injection of Aconitine in the Locus Coeruleus in Unanesthetized Rats." Fed. Proc 37:687, 1987 (Abstract)

Perlman R, Hook B, Marchlinski F: "Rate Dependent Changes in Bipolar Pacing Thresholds in a Combined Antitachycardia Pacemaker/Defibrillator. PACE 13:539, 1990 (Abstract)

Perlman R, Poll D, Josephson M, Simson M, Marchlinski F: "Relationship of Signal Averaged ECG and Late Epicardial Electrograms to Inducible Arrhythmias in Patients with Idiopathic Dilated Cardiomyopathy." Circ. Supp. III 82:354, 1990 (Abstract)

Perlman R, Miller J, Kindwall K, Buxton A, Josephson M, Marchlinski F: "Abnormal Epicardial and Endocardial Electrograms in Patients with Idiopathic Dilated Cardiomyopathy: Relationship to Arrhythmias." Circ. Supp. III 82:708, 1990 (Abstract)

Hook B, Perlman R, Johnson N, Flores B, Marchlinski F: " Value of Stored Electrograms and Programmable Sensing Criteria in Optimizing Management of Patients Receiving Pacing and Shocks for Asymptomatic Arrhythmias." J. Am. Coll. Cardiology 17:85A, 1991 (Abstract)

Baron M, Perlman R, Levitt M: "Paranoid Schizophrenia and Platelet MAO Activity." Am. J. Psychiatry 137:1465-1466, 1980

Baron M, Perlman R, Levitt M: "Human Platelet Monoamine Oxidase and the Menstrual Cycle." Psychiatry Research 3:1323-327, 1980

Baron M, Perlman R, Levitt M: "Low Platelet Monoamine Oxidase Activity: A Possible Biochemical Correlate of Borderline Schizophrenia." Psychiatry Research 3:329-335, 1980

Baron M, Perlman R, Levitt M: "Plasma DBH Activity: Relation to Genetic Factors in Schizophrenia." Communications in Psychopharmacology 4:197-202, 1980

Baron M, Perlman R, Levitt M: "Platelet Monoamine Oxidase Values and Genetic Heterogeneity in Schizophrenia Research." JAMA 246:1418-1421, 1981

Baron M, Perlman R, Levitt M, Meltzer H, Gruen R, Asnis L: "Plasma Copper and Dopamine-Beta-Hydroxylase in Schizophrenia." Biological Psychiatry 17:115-120, 1982

Perlman R, Guideri G: "Cardiovascular Changes Produced by the Injection of Aconitine at the Area of the Locus Coeruleus in Unanesthetized Rats." Arch. In. Pharmacodyn. 268:202-215, 1984

Hook S, Perlman R, Callans Dr, Hanna M, Kleiman R, Flores B, Marchlinski F: "Acute and Chronic Cycle Length Dependent Increase in Ventricular Pacing Threshold." PACE Pacing Clin Electrophysiology 1992 October; 15(10 pt 1):1437-44

Sabatine MS, Cannon CP, Gibson CM, Lo'pez-Sendo'n JL, Montalescot G, Theroux P, Claeys MJ, Cools F, Hill KA, Skene AM, McCabe CH, Braunwald E for the Clarity -TIMI 28 Investigators: "Addition of Clopidogrel to Aspirin and Fibrinolytic Therapy for Myocardial Infarction with ST-Segment Elevation." The New England Journal of Medicine Vol. 352, 12:1-11, March 24, 2005.

Lincoff A., Harrington R, Califf R, Hochman J, Guerci A, Ohman E., Pepine C, Kopecky S, Kleiman N, Pacchiana C, Berdan L, Kitt M, Simoons M, Topol E for the PURSUIT Trial Investigators: "Management of Patients With Acute Coronary Syndromes in the United States by Platelet Glycoprotein IIb/IIIa Inhibition". Circulation Vol 102, 10:1093-1100, September 2000.

The PURSUIT TRIAL INVESTIGATORS, "Inhibition of Platelet Glycoprotein IIb/IIIa with Eptifibatide in Patients with Acute Coronary Syndromes". The New England Journal of Medicine Vol 339: 436-443, August 13, 1998.

LECTURES

October 9, 1992
"Signal Averaged ECG." Seminar in Arrhythmia Management, The Heart Center at Sinai, Sinai Hospital, Baltimore, MD

October 23, 1993
Supraventricular Tachycardias: Diagnosis and Drug Therapy." Seminar in Arrhythmia Management, The Heart Center at Sinai, Sinai Hospital, Baltimore, MD

PEER REVIEW

INTERNATIONAL

Perlman R, Poll D, Josephson M, Simson M, Marchlinski F: "Relationship of Signal Averaged ECG and Late Epicardial Electrograms to Inducible Arrhythmias in Patients with Idiopathic Dilated Cardiomyopathy." (Abstract) AHA 63rd Scientific Sessions (Dallas, TX), Department of Cardiology, University of Pennsylvania, November 13, 1990

Perlman R, Miller J, Kindwall K, Buxton A, Josephson M, Marchlinski F: "Abnormal Epicardial and Endocardial Electrograms in Patients with Idiopathic Dilated Cardiomyopathy: Relationship to Arrhythmias." (Abstract) AHA 63rd Scientific Sessions (Dallas, TX), Department of Cardiology, University of Pennsylvania, November 15, 1990

Perlman R, Hook B, Marchlinski F: "Rate Dependent Changes in Bipolar Pacing Thresholds in a Combined Antitachycardia Pacemaker/ Defibrillator." (Abstract) NASPE 11th Annual Scientific Session (San Diego, CA), Department of Cardiology, University of Pennsylvania, May 31, 1990

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